TTYH1 Antibody, Biotin conjugated

Code CSB-PA867139LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TTYH1 Polyclonal antibody
Uniprot No.
Target Names
TTYH1
Alternative Names
TTYH1; Protein tweety homolog 1; hTTY1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein tweety homolog 1 protein (50-178AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probable chloride channel. May be involved in cell adhesion.; Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
Gene References into Functions
  1. In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells. PMID: 28607172
  2. TTYH1 was not expressed in either the malignant or the control samples PMID: 25182704
  3. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor. PMID: 24316981
  4. Nedd4-2 differentially interacts with and regulates TTYH1-3 PMID: 18577513
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Tweety family
Tissue Specificity
Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung.
Database Links

HGNC: 13476

OMIM: 605784

KEGG: hsa:57348

UniGene: Hs.268728

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